5 EASY FACTS ABOUT PKRRATING DESCRIBED

The activated enzyme then phosphorylates its major substrate, the translational initiation element eIF2α. The resulting translational arrest blocks viral replication. PKR belongs to a conserved loved ones of four protein kinases (PKR, PERK, GCN2, HRI) that every one phosphorylate eIF2α in reaction to distinct stimuli12, triggering the built-in he